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Nordic Signal Labs

Semax

€129.95

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Semax in a ready-mixed pen with 10 mg of active peptide. Read about its structure, neurotrophins and studies of nerve-cell signalling.

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Product details

Product information

About the substance

Semax is a synthetic peptide consisting of seven amino acids. Its structure combines the ACTH(4–7) fragment with Pro-Gly-Pro, often written ACTH(4–7)-Pro-Gly-Pro. This describes its molecular design, not a mixture of ACTH and separate growth factors. Semax is discussed in neurobiology because experiments have examined how it influences signals associated with nerve cells. Understanding those signals helps separate the identity of the substance from claims about a finished product.

How it works

BDNF and NGF belong to a family of signalling proteins called neurotrophins. BDNF stands for brain-derived neurotrophic factor; NGF means nerve growth factor. These proteins participate in the development, maintenance and adaptation of nerve cells. Receptors on cells receive signals and pass them into the cell. Gene expression describes how cells use genetic instructions to make molecules. Semax studies have examined changes in this system; the pen itself contains Semax, not BDNF or NGF. A change in gene activity is one biological measurement, not a direct measurement of memory or focus.

What studies have examined

Agapova and colleagues (2007) observed region-dependent changes in BDNF and NGF gene expression in rat brains after Semax administration. Dmitrieva and colleagues (2010) examined rats with experimentally reduced cerebral blood flow and reported changes in neurotrophin and receptor gene expression. The studies involved different biological conditions; they did not test this commercial pen.

How to interpret the findings

The findings help explain why Semax is discussed in relation to nerve-cell signalling and responses to injury. They do not establish that this pen improves attention, learning or everyday mental performance, or treats ADHD or neurological disease. Brain region, experimental model, formulation and delivery method affect how results should be interpreted. A study using a different preparation cannot establish how this pen behaves. Evidence for a biological mechanism, evidence for a clinical benefit and verification of a particular batch answer three different questions.

Product specifications

  • Format: Ready-mixed peptide pen
  • Stated total quantity: 10 mg

This pen contains 10 mg of active Semax. The figure describes the peptide quantity in the entire pen, not the weight or volume of the liquid. A 10 mg product contains more labelled peptide than a 2 mg product; this does not mean a fivefold effect or specify a dose. Liquid volume is needed to calculate mg/ml, and a pen-specific specification is needed to establish output per setting.

Questions and answers

What does 10 mg mean?

It is the amount of active Semax in the whole pen. It is not 10 ml and does not specify the amount per setting.

Does the pen contain BDNF or NGF?

No. The active peptide is Semax. BDNF and NGF are signalling proteins discussed when explaining the biological studies.

What does neuroplasticity mean?

It describes the ability of nerve cells and their connections to change with activity and experience. Mentioning this process does not establish that a product improves learning.

Does a larger pen mean a stronger effect?

A larger labelled mg quantity means more active peptide in the pen. It does not establish concentration, a suitable dose or a greater effect.

Documentation and handling

For details about identity, content and the available certificate, contact info@nordicpept.com and specify the product and batch. Follow the storage and handling instructions supplied with the actual product. A publication about an ingredient is not a certificate for a finished pen.

Selected studies

Strength

10 mg

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